Investor Centre

Our broad clinical and preclinical pipeline in brain disorders focuses on indications including addiction, anxiety, fatigue, narcolepsy and glioblastoma.
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0.17 GBX Volume: 4,770,131 Market Capitalisation (m) £4.64
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Diversified portfolio in high demand therapeutic areas

Diversified portfolio in high demand therapeutic areas


  • Focus on brain disorders

  • Pre-clinical CNS pipeline in indications with high unmet need – addiction, anxiety, narcolepsy

  • Clinical stage, grant funded collaboration with Erasmus Medical Centre for SFX-01 in glioblastoma.

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Significant market potential

Significant market potential


  • Near clinic-ready CNS assets offer opportunity to build substantial value quickly

  • Addiction market alone currently worth $40bn worldwide

  • Out-licensing transactions at early and mid-stage development in the £00million range

  • Lack of suitable drug candidates currently in development for addictive behaviours

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Compelling data

Compelling data


  • Heavily de-risked lead CNS programme – an Ox-1 inhibitor – with short path to key inflection point of clinical readiness

  • Ox-1 antagonist (blocker) exhibits best-in-class potential

  • DAT inhibitor candidate molecule at late preclinical stage targeting fatigue and narcolepsy

  • High quality clinical and pre-clinical data on all assets, validated by third party experts

  • Published in peer reviewed journals

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Lead programmes funded to key inflection points

Lead programmes funded to key inflection points


  • Ox-1 programme funded to clinical trial- readiness – allowing us to unlock potential commercial opportunities

  • SFX-01 programme with Erasmus Medical Centre funded by KWF Dutch Cancer Society

  • Cash runway to end 2026 – amongst the longest cash runways of UK and European listed biotech companies

  • Capital efficient, virtual company with low overheads

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Experienced leadership team

Experienced leadership team


  • Leadership team brings extensive experience from across R&D, business development, biotech company building and successful exits

  • Collectively delivered numerous biotech licensing deals and developed drugs to market

  • Track record of effective company financing via both capital markets and non-dilutive grant funding

TheraCryf plc Investor Presentation

28 - September - 2026
TheraCryf shares the latest corporate presentation following announcement of the final results to end March 2026

Investor Meet Company - TheraCryf

28 - September - 2026
IMC video following the announcement of TheraCryf's final results for the year ended 31 March 2026

TheraCryf plc Notice of AGM

30 - September - 2026
Notice of AGM and Proxy form published ahead of TheraCryf's AGM on the 22nd October

Major Shareholders

Current ShareholderNumber of sharesPercentage holding
Northern Standard Limited568,958,45620.82%
First Equity Limited310,700,00011.37%
T and I Limited160,000,0005.86%
Hargreaves Lansdown Asset Management97,169,8193.56%
Spreadex Limited80,050,0012.93%
A Leach80,000,0002.93%
S Gibeon71,400,0002.61%
J. R. Kight70,000,0002.56%
A J Bell Securities61,210,2952.24%
P Byrne60,000,0002.20%
K Byrne60,000,0002.20%
TheraCryf plc Directors and Related Parties54,397,6801.99%
Interactive Investor46,024,6391.68%
N Burton40,000,0001.46%
RAB Capital34,750,0001.27%
N Hawkins30,000,0001.10%
Charles Stanley (London)29,973,5461.10%
Halifax Share Dealing29,507,2211.08%
Barclay's Wealth (London)28,745,7061.05%
Turner Pope Investments26,000,0000.95%
C M Holmes25,500,0000.93%
Peel Hunt24,928,8540.91%
Octopus Investments21,875,0000.80%
C G Poll21,500,0000.79%
Rathbone Investment Management Ltd21,432,4480.78%
The number of ordinary shares in issue is 2,732,297,067. Directors hold 54,397,680 (1.99%) and 2,677,899,387 are in public hands. The Company does not hold any shares in the Treasury. Figures last updated 9 September 2026.
Last updated 09 October 2026