Investor Centre
Our broad clinical and preclinical pipeline in oncology and behavioural brain disorders focuses on indications including glioblastoma, neurodevelopmental disorders, addiction, anxiety, fatigue and narcolepsy.
Diversified portfolio in high demand therapeutic areas
Diversified portfolio in high demand therapeutic areas
- Focus on brain disorders
- Pre-clinical CNS pipeline in indications with high unmet need – addiction, anxiety, narcolepsy
- Clinical stage, grant funded collaboration with Erasmus Medical Centre for SFX-01 in glioblastoma.
Significant market potential
Significant market potential
- Near clinic-ready CNS assets offer opportunity to build substantial value quickly
- Addiction market alone currently worth $40bn worldwide
- Out-licensing transactions at early and mid-stage development in the £00million range
- Lack of suitable drug candidates currently in development for addictive behaviours
Compelling data
Compelling data
- Heavily de-risked lead CNS programme – an Ox-1 inhibitor – with short path to key inflection point of clinical readiness
- Ox-1 antagonist (blocker) exhibits best-in-class potential
- DAT inhibitor candidate molecule at late preclinical stage targeting fatigue and narcolepsy
- High quality clinical and pre-clinical data on all assets, validated by third party experts
- Published in peer reviewed journals
Lead programmes funded to key inflection points
Lead programmes funded to key inflection points
- Ox-1 programme funded to clinical trial- readiness – allowing us to unlock potential commercial opportunities
- SFX-01 programme with Erasmus Medical Centre funded by KWF Dutch Cancer Society
- Cash runway to end 2026 – amongst the longest cash runways of UK and European listed biotech companies
- Capital efficient, virtual company with low overheads
Experienced leadership team
Experienced leadership team
- Leadership team brings extensive experience from across R&D, business development, biotech company building and successful exits
- Collectively delivered numerous biotech licensing deals and developed drugs to market
- Track record of effective company financing via both capital markets and non-dilutive grant funding
TheraCryf plc Investor Presentation

09 - July - 2025
TheraCryf shares the corporate presentation following the AGM held on the 9th July 2025.
Major Shareholders
Current Shareholder | Number of shares | Percentage holding |
---|---|---|
Northern Standard Limited | 422,727,272 | 19.67% |
First Equity Limited | 179,000,000 | 8.33% |
T and I Limited | 160,000,000 | 7.45% |
Oberon Investments Limited | 80,475,000 | 3.74% |
Spreadex Limited | 80,009,545 | 3.72% |
A Leach | 80,000,000 | 3.72% |
S Gibeon | 71,400,000 | 3.32% |
J. R. Kight | 56,100,000 | 2.61% |
Rathbones Investment Management Ltd | 24,835,704 | 1.16% |
Octopus Investments | 21,875,000 | 1.02% |
Vulpes Investment Management Pte Ltd | 20,554,191 | 0.96% |
Seneca Partners Limited | 16,301,456 | 0.76% |
The number of ordinary shares in issue is 2,148,963,739. Directors hold 13,184,793 and 2,135,778,946 are in public hands. The Company does not hold any shares in the Treasury.